Borussia Dortmund will announce the departure of coach Jurgen Klopp at a news conference at 12:30 BST.
The 47-year-old German will leave the Bundesliga club at the end of the season, having asked to be released from his contract, which is due to run until 2018.
German daily Bild said former Mainz 05 coach Thomas Tuchel is to replace him.
Klopp has coached Dortmund since 2008, taking them to two league titles and the Champions League final in 2012-13.
According to Bild, Klopp will take some time away from football before returning to management.
He has frequently been linked with Premier League clubs, including Manchester United before the appointment of Louis van Gaal, Arsenal during lean spells at the Emirates, and latterly with defending champions Manchester City, who have dropped to fourth in the table, 12 points behind leaders Chelsea.
Regarded as one of the most talented coaches in European football, the charismatic Klopp led Dortmund to two Bundesliga titles in addition to the Champions League final, in which they were beaten 2-1 by fellow Germans Bayern Munich at Wembley.
However, this term Dortmund have encountered a difficult period, and were at one stage bottom of the table before reaching their current position of 10th, 37 points behind leaders Bayern.
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